Plasma Cell Lineage Images

Plasma Cell Lineage Images : Plasma cells are developed from B lymphocytes, a type of white blood cells that is generated in the bone marrow. The plasma cells produce antibodies to fight with bacteria and viruses and stop infection and disease. Multiple myeloma is a cancer of plasma cells that collections of abnormal plasma cells (myeloma cells) accumulate in the bone marrow. The definitive diagnosis of multiple myeloma is done by searching for myeloma cells in the bone marrow slides through a Microscope.

The database consist of bone marrow aspiration slides which was digitized by a Nikon1 V1, high-resolution digital camera coupled to Nikon Eclipse 50i light microscope and a 100 power objective yielded a total magnification of 1000. Also, it should be mentioned that the database is taken in different time from different bone marrow smears which are provided by different technicians.

It consists of bone marrow smear images which are provided by contributions of Pathology department of Alzahra Hospital, Isfahan, Iran. The database is composed of 50 bone marrow smear images.

The following paper is in this regard (please cite the paper if you used this dataset):
Zahra Saeedizadeh, Alireza Mehri Dehnavi, Ardeshir Talebi, Hossein Rabbani, Omid Sarrafzadeh & Alireza Vard, “Automatic Recognition of Myeloma Cells in Microscopic Images using Bottleneck algorithm, Modified Watershed and SVM Classifier”, Journal of microscopy, 2015.

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